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24 Eyl%u00fcl - September / Ekim - October 2024 Makale / Articlebitkisel materyaller haz%u0131rlan%u0131r ve uygun b%u00fcy%u00fckl%u00fckte par%u00e7alanmaktad%u0131r.Ekstraksiyon: Haz%u0131rlanan materyaller, s%u00fcperkritik CO%u2082 ile bir ekstrakt%u00f6rde i%u015flenir. Bu i%u015flem s%u0131ras%u0131nda s%u0131cakl%u0131k ve bas%u0131n%u00e7 kontroll%u00fc olarak ayarlan%u0131r. CO%u2082%u2019nin s%u00fcperkritik faz%u0131, vitaminleri %u00e7%u00f6zerek ayr%u0131%u015ft%u0131rmaktad%u0131r.Separasyon: Ekstrakt%u00f6rde elde edilen kar%u0131%u015f%u0131m, CO%u2082 ve vitaminlerin ayr%u0131%u015ft%u0131r%u0131ld%u0131%u011f%u0131 bir ayr%u0131%u015ft%u0131r%u0131c%u0131ya y%u00f6nlendirilir. CO%u2082%u2019nin bas%u0131nc%u0131 d%u00fc%u015f%u00fcr%u00fcld%u00fc%u011f%u00fcnde, vitaminler %u00e7%u00f6z%u00fcn%u00fcr ve toplama haznesine ge%u00e7mektedir.Son %u0130%u015flem: Toplanan vitaminler, saf ve konsantre bir formda olur. C ve E vitaminleri genellikle toz formunda ya da ya%u011f bazl%u0131 %u00fcr%u00fcnler halinde kullan%u0131labilmektedir.S%u00fcperkritik ekstraksiyon tekni%u011fi, y%u00fcksek safl%u0131kta ve kaliteli %u00fcr%u00fcnler elde edilmesini sa%u011flar, %u00e7evre dostudur ve y%u00fcksek verimlilik sunar. G%u0131da end%u00fcstrisinde, kozmetik %u00fcr%u00fcnlerinde ve besin takviyelerinde geni%u015f bir uygulama yelpazesi bulur. C ve E vitaminlerinin saf ve etkili formlar%u0131n%u0131 %u00fcretmek i%u00e7in tercih edilen %u00f6nemli bir tekniktir.Elektrospinning Tekni%u011fiyle Transdermal Bant EldesiD%u00f6ner tambura yerle%u015ftirilen PU film %u00fczerine %u015f%u0131r%u0131ngaya %u00e7ekilen C ve E vitamini sol%u00fcsyonu 30 kV voltaj, 1.5 ml/saat besleme h%u0131z%u0131, 12 cm %u00e7al%u0131%u015fma mesafesi uygulanarak p%u00fcsk%u00fcrtme yap%u0131larak kaplama sa%u011flanm%u0131%u015ft%u0131r. Elde edilen %u00fcr%u00fcn vakum et%u00fcv%u00fcnde kurutulmu%u015ftur. Kuruma sonras%u0131 yap%u0131%u015fkan s%u00fcr%u00fclerek %u00fczerine ka%u011f%u0131t materyal kapat%u0131lm%u0131%u015ft%u0131r. Extraction: The prepared materials are processed in an extractor with supercritical CO%u2082. During this process, temperature and pressure are controlled. The supercritical phase of CO%u2082 dissolves and separates the vitamins.Separation: The mixture obtained from the extractor is directed to a separator where CO%u2082 and vitamins are separated. When the pressure of CO%u2082 is reduced, the vitamins dissolve and move to the collection chamber.Final Processing: The collected vitamins are obtained in a pure and concentrated form. C and E vitamins are typically used in powder form or as oil-based products.The supercritical extraction technique ensures the production of high-purity and high-quality products, is environmentally friendly, and offers high efficiency. It finds wide applications in the food industry, cosmetics, and dietary supplements. It is an important technique for producing pure and effective forms of C and E vitamins.Production of Transdermal Patches Using Electrospinning TechniqueA solution of C and E vitamins drawn into a syringe was sprayed onto a PU film placed on a rotating drum, using 30 kV voltage, a 1.5 ml/hour feed rate, and a 12 cm working distance to achieve coating. The obtained product was dried in a vacuum oven. After drying, an adhesive was applied, and a paper material was placed on top.%u015eekil 4. S%u00fcperkritik ekstrasiyon tekni%u011fiyle etken madde eldesi [5]Figure 4. Active Ingredient Extraction Using Supercritical Extraction Technique [5]