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Makale / Article20 Eyl%u00fcl - September / Ekim - October 2024 Giri%u015fTransdermal bantlar, ila%u00e7lar%u0131n cilt yoluyla sistemik dola%u015f%u0131ma ge%u00e7mesini sa%u011flayan bir sistem olarak, modern t%u0131bb%u0131n %u00f6nemli bir bile%u015fenini olu%u015fturmaktad%u0131r. Bu sistemler, genellikle aktif maddeleri cilt %u00fczerine uygulanan bir bant arac%u0131l%u0131%u011f%u0131yla s%u00fcrekli ve kontroll%u00fc bir %u015fekilde salmak i%u00e7in tasarlanm%u0131%u015ft%u0131r. Son y%u0131llarda, transdermal bant teknolojisinde kaydedilen ilerlemeler, %u00e7e%u015fitli materyallerin ve uygulama stratejilerinin geli%u015ftirilmesini m%u00fcmk%u00fcn k%u0131lm%u0131%u015ft%u0131r. %u00d6zellikle poli%u00fcretan (PU) tabanl%u0131 materyaller, transdermal sistemlerin tasar%u0131m%u0131nda %u00f6nemli bir rol oynamaktad%u0131r [1,2].PU, y%u00fcksek esneklik, dayan%u0131kl%u0131l%u0131k ve biyouyumluluk gibi %u00f6zellikleri sayesinde transdermal bantlar%u0131n %u00fcretiminde tercih edilen bir malzemedir. Bu materyalin kullan%u0131m%u0131, bantlar%u0131n ciltle uyumunu ve ila%u00e7 sal%u0131n%u0131m%u0131n%u0131 optimize etmeye y%u00f6nelik %u00e7e%u015fitli stratejilerin geli%u015ftirilmesini sa%u011flam%u0131%u015ft%u0131r. PU tabanl%u0131 transdermal bantlar, IntroductionTransdermal patches are an important component of modern medicine, serving as a system that allows drugs to enter systemic circulation through the skin. These systems are typically designed to release active substances continuously and controllably via a patch applied to the skin. In recent years, advancements in transdermal patch technology have enabled the development of various materials and application strategies. In particular, polyurethane (PU)-based materials play a significant role in the design of transdermal systems [1,2].PU is a preferred material for the production of transdermal patches due to its properties such as high flexibility, durability, and biocompatibility. The use of this material has enabled the development of various strategies to optimize the patches' compatibility with the skin and drug release. PU-based transdermal patches are utilized in Poli%u00fcretan Tabanl%u0131 Nanoteknolojik Transdermal BantPolyurethane-Based Nanotechnolog%u0131cal Transdermal PatchErdi Bulu%u015f%u00d6%u011fretim G%u00f6revlisi / Lecturer %u0130stanbul Arel %u00dcniversitesi ArelPOTKAMIstanbul Arel University ArelPOTKAM %u015eekil 1. Transdermal bant [1] / Figure 1. Transdermal Patch [1]