Page 23 - Demo

21hem ila%u00e7 sal%u0131n%u0131m%u0131n%u0131 d%u00fczenlemek hem de ciltle temas%u0131n%u0131 iyile%u015ftirmek amac%u0131yla %u00e7e%u015fitli form%u00fclasyonlarda kullan%u0131lmaktad%u0131r.Elektrospinning teknolojisi, nanoyap%u0131l%u0131 liflerin %u00fcretiminde devrim niteli%u011finde bir y%u00f6ntem olarak kabul edilmektedir. Bu teknoloji, y%u00fcksek voltajl%u0131 elektrik alanlar%u0131n%u0131n kullan%u0131lmas%u0131yla polimer %u00e7%u00f6zeltisinin ince lifler halinde %u00e7ekilmesini sa%u011flar ve bu s%u00fcre%u00e7 sonucunda y%u00fcksek y%u00fczey alan%u0131na sahip nanolifler elde edilmektedir. Elektrospinning, %u00f6zellikle medikal uygulamalarda ve transdermal sistemlerde geni%u015f bir kullan%u0131m potansiyeline sahiptir. Elektrospinning'in temel prensibi, bir polimer %u00e7%u00f6zeltisinin bir i%u011fne veya memeden, y%u00fcksek bir elektrik potansiyeli uygulanarak ince lifler haline %u00e7ekilmesidir. Elektrik alan%u0131, %u00e7%u00f6zeltinin damlac%u0131klar%u0131n%u0131n ince bir iplik%u00e7ik haline d%u00f6n%u00fc%u015fmesini ve bu iplik%u00e7iklerin havada kuruyarak nanoyap%u0131l%u0131 liflere d%u00f6n%u00fc%u015fmesini sa%u011flamaktad%u0131r. Bu y%u00f6ntemle elde edilen lifler, mikrometre ve nanometre aral%u0131%u011f%u0131nda %u00e7aplara sahip olup, y%u00fcksek y%u00fczey alan%u0131 ve poroziteye sahiptir. Liflerin d%u00fczenli bir %u015fekilde dizilmesi ve y%u00fcksek doku uyumlulu%u011fu, bu teknolojiyi medikal ve biyom%u00fchendislik uygulamalar%u0131 i%u00e7in ideal k%u0131lmaktad%u0131r.Transdermal bant %u00fcretiminde elektrospinning teknolojisinin %u00f6nemi giderek artmaktad%u0131r. Bu teknoloji, transdermal sistemlerin performans%u0131n%u0131 %u00f6nemli %u00f6l%u00e7%u00fcde iyile%u015ftirme potansiyeline sahiptir. %u00d6zellikle, elektrospinning ile elde edilen nanolifler, ila%u00e7 sal%u0131n%u0131m%u0131n%u0131 kontrol etmek ve art%u0131rmak i%u00e7in kullan%u0131lan ta%u015f%u0131y%u0131c%u0131 matrisler olarak i%u015flev g%u00f6rebilir. Nanoyap%u0131l%u0131 liflerin y%u00fcksek y%u00fczey alan%u0131 ve porozite %u00f6zellikleri, ila%u00e7lar%u0131n s%u00fcrekli ve kontroll%u00fc bir %u015fekilde sal%u0131n%u0131m%u0131n%u0131 sa%u011flamak i%u00e7in gerekli olan %u00f6zellikleri sunar. Ayr%u0131ca, elektrospinning ile %u00fcretilen bantlar%u0131n various formulations both to regulate drug release and to improve skin contact.Electrospinning technology is considered a revolutionary method for the production of nanostructured fibers. This technology enables the drawing of a polymer solution into fine fibers using high-voltage electric fields, resulting in nanofibers with a high surface area. Electrospinning has a broad potential for use, especially in medical applications and transdermal systems. The fundamental principle of electrospinning is the drawing of a polymer solution into fine fibers by applying a high electric potential through a needle or nozzle. The electric field causes the solution droplets to elongate into a fine thread, which then dries in the air to form nanostructured fibers. The fibers produced by this method have diameters in the micrometer and nanometer range, offering high surface area and porosity. The regular arrangement of the fibers and their high tissue compatibility make this technology ideal for medical and biomedical engineering applications.The importance of electrospinning technology in the production of transdermal patches is increasingly recognized. This technology has significant potential to greatly improve the performance of transdermal systems. Specifically, nanofibers obtained through electrospinning can function as carrier matrices used to control and enhance drug release. The high surface area and porosity of nanostructured fibers provide the necessary characteristics for continuous and controlled drug release. Additionally, the mechanical flexibility and biocompatibility of electroMakale / Article%u015eekil 2. PU tabanl%u0131 transdermal bant [3] / Figure 2. PU-Based Transdermal Patch [3]%u015eekil 3. Elektrospinning teknolojisi ile nanoliflerin g%u00f6r%u00fcnt%u00fcs%u00fc [4] Figure 3. Image of Nanofibers Produced by Electrospinning Technology [4]