Page 63 - Demo

SYN%u00ae-COLL CB, k%u00fc%u00e7%u00fck bir sentetik peptit molek%u00fcl%u00fcd%u00fcr. Ciltte kollajen sentezinde %u00f6nemli bir element olan d%u00f6n%u00fc%u015ft%u00fcr%u00fcc%u00fc b%u00fcy%u00fcme fakt%u00f6r%u00fc beta, TGF-%u03b2%u2019y%u0131 (doku b%u00fcy%u00fcme fakt%u00f6r%u00fc) aktive etmek i%u00e7in v%u00fccudun do%u011fal mekanizmas%u0131n%u0131 taklit ederek kolajeni art%u0131r%u0131r. Ayr%u0131ca matriks metaloproteinazlar%u0131 (MMP) inhibe ederek kolajeni bozulmaya kar%u015f%u0131 korur. Bu iki aktivite de cildin yap%u0131sal b%u00fct%u00fcnl%u00fc%u011f%u00fcn%u00fc tam olarak korumak i%u00e7in sinerjik olarak %u00e7al%u0131%u015f%u0131r. Trombospondin (TSP-1), kollajen sentezinde anahtar element olarak bilinen TGF-%u03b2%u2019n%u0131n latent (ancak biyolojik olarak aktif) formunu aktive eden %u00e7ok i%u015flevli bir proteindir. Bu yenilik%u00e7i %u00e7al%u0131%u015fma mekanizmas%u0131, SYN%u00ae-COLL CB%u2019yi piyasadaki ilk TGF-%u03b2 g%u00fc%u00e7lendirici yapm%u0131%u015ft%u0131r.SYN%u00ae-COLL CB%u2019nin In Vivo Etkinlik %u00c7al%u0131%u015fmas%u0131Dsm-firmenich taraf%u0131ndan %u00c7inli g%u00f6n%u00fcll%u00fcler %u00fczerinde yeni bir in vivo %u00e7al%u0131%u015fma ger%u00e7ekle%u015ftirilmi%u015ftir. Foto ya%u015flanman%u0131n etkileriyle m%u00fccadele ederken bile %u00e7izgi ve k%u0131r%u0131%u015f%u0131kl%u0131klar%u0131n g%u00f6r%u00fcn%u00fcm%u00fcnde azalma oldu%u011funu ortaya %u00e7%u0131karm%u0131%u015ft%u0131r. Sonu%u00e7lar sadece 1 ayda elde edilmi%u015f olup, SYN%u00ae-COLL CB, benzer rakip %u00fcr%u00fcnle kar%u015f%u0131la%u015ft%u0131r%u0131ld%u0131%u011f%u0131nda daha p%u00fcr%u00fczs%u00fcz, daha gen%u00e7 g%u00f6r%u00fcnen bir cilt i%u00e7in daha dolgun, %u015fekillendirilmi%u015f bir g%u00f6r%u00fcn%u00fcm ve s%u0131k%u0131la%u015fm%u0131%u015f g%u00f6zenek g%u00f6r%u00fcn%u00fcm%u00fc sa%u011flamaya yard%u0131mc%u0131 olmu%u015ftur. SYN%u00ae-COLL CB%u2019nin etkinli%u011fini rakip %u00fcr%u00fcnle k%u0131yaslay%u0131p %u00f6l%u00e7mek i%u00e7in, ya%u015f ortalamas%u0131 46 olan 31 olan %u00c7inli kad%u0131n g%u00f6n%u00fcll%u00fc aras%u0131nda sekiz haftal%u0131k, y%u00fcz%u00fcn yar%u0131s%u0131nda, randomize bir %u00e7al%u0131%u015fma ger%u00e7ekle%u015ftirilmi%u015ftir. %2,5 SYN%u00ae-COLL CB i%u00e7eren bir nemlendirici g%u00fcnde iki kez uygulanm%u0131%u015f ve k%u0131r%u0131%u015f%u0131kl%u0131k de%u011ferlendirmesi FOITS tekni%u011fi ile %u00f6l%u00e7%u00fclm%u00fc%u015ft%u00fcr. SYN%u00ae-COLL CB is a small molecular synthetic peptide, firstly boosts collagen by mimicking the human body%u2019s own mechanism to activate latent transforming growth factor beta, TGF-%u03b2 (tissue growth factor), a key element in the synthesis of collagen. It also protects collagen from degradation through the inhibition of matrix metalloproteinases (MMP). Both activities work synergistically to maintain complete structural integrity of the skin. Thrombospondin (TSP-1) is a multifunctional protein that activates the latent (but biologically in active) form of TGF-%u03b2, known as the key element in the synthesis of collagen. This innovative mechanism made SYN%u00ae-COLL CB the first TGF-%u03b2 booster on the market.In Vivo Efficacy Study of SYN%u00ae-COLL CB A new in vivo study was conducted by dsm-firmenich on Chinese volunteers. It revealed a reduction in the appearance of lines and wrinkles, even when combating the effects of photo-aging. The results were achieved in just one month. SYN%u00ae-COLL CB helps reveal a more lifted, sculpted look, and refined pore appearance for smoother, younger-looking skin compared to the competitive benchmark. To measure SYN%u00ae-COLL CB%u2019s efficacy vs competitive benchmark, an eight-week, split-face, randomized study was conducted amongst 31 female Chinese volunteers with an average age of 46. A moisturizer containing 2.5% of active ingredient was applied twice daily. Wrinkle evaluation was measured by the FOITS technique. Makale / Article61Grafik 1. 4 haftada k%u0131r%u0131%u015f%u0131kl%u0131k azaltma de%u011ferlendirmesi sonucunu g%u00f6sterir. SYN%u00ae-COLL CB, rakip %u00fcr%u00fcn%u00fc b%u00fcy%u00fck %u00f6l%u00e7%u00fcde geride b%u0131rakm%u0131%u015ft%u0131r. Bir ayda %15 daha iyi etkinlik g%u00f6stermektedir.Graph 1. Wrinkle reduction evaluation in 4 weeks. SYN%u00ae-COLL CB significantly out-performs the benchmark. It shows 15% better efficacy in one month